ASPP1抗体,p53凋亡刺激蛋白1抗体
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上海博研生物优质提供“Anti-ASPP1抗体,p53凋亡刺激蛋白1抗体”，抗体产品3个月质保，保证实验效果，抗体产品有任何质量问题，一经查实，免费调换。欢迎来电咨询！
产品详细信息
Anti-ASPP1抗体,p53凋亡刺激蛋白1抗体产品详细资料
产品编号 BYK-1282R
英文名称 ASPP1
中文名称 p53凋亡刺激蛋白1抗体
别名 p53BP2 like; p85; PPP1R13B; apoptosis stimulating protein of P53 1; Apoptosis-stimulating of p53 protein 2; Tumor suppressor p53-binding protein 2; p53-binding protein 2; p53BP2; 53BP2; Bcl2-binding protein; Bbp; Renal carcinoma antigen NY-REN-51.
研究领域 肿瘤细胞凋亡
分子量 120kDa
抗体来源 Mouse or Rabbit
克隆类型 Monoclonal orPolyclonal
产品应用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC此产品应用不做依据，具体产品应用与实验稀释比请来电咨询！021-60340810
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性状 Lyophilized or Liquid
浓度 1mg/1ml
亚型 IgG
纯化方法 affinity purified by Protein G
储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Anti-ASPP1抗体,p53凋亡刺激蛋白1抗体产品介绍
iASPP (inhibitor of apoptosis stimulating protein of p53, RelA-associated inhibitor (RAI), NFKap B-interacting protein 1, protein phosphatase 1 regulatory subunit 13-like, PPP1R13L) is the third member of the ASPP family of proteins. Unlike ASPP1 and ASPP2, which interact with p53 and enhance its ability to induce apoptosis, iASPP inhibits apoptosis induced by p53 overexpression. iASPP has been identified in a yeast-two hybrid screen as an interacting protein of the p65 subunit of NFKap B (RelA),3 interacts with NFKap B in vivo, and acts as an efficient inhibitor of HIV-1 gene expression in which both NFKap b and Sp1 play major roles. iASPP expression is upregulated in human breast carcinomas expressing wild-type p53, and gene overexpression may play an important role in the leukemogenesis and/or progression of acute leukemia.
此相关标记有：AlexaFluor350标记、AlexaFluor488标记、AlexaFluor555标记、AlexaFluor647标记、AP标记、APC标记、Biotin标记、Cy3标记、Cy5标记、Cy5.5标记、Cy7标记、FITC标记、Gold标记、HRP标记、PE标记、PE-Cy3标记、PE-CY5标记、PE-CY5.5标记、PE-CY7标记、RBITC标记
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